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Pollution on your commute, how you went to bed late last night, even what you ate for lunch… Daily choices and the environment affect your overall health. And when it comes to your skin, they can even increasing signs of aging.

These everyday elements make up what’s called an exposome. Learn the definition of an exposome, how it affects your skin, and some advice from a dermatologist on how you can fight the disease.

What are you looking for?

What is Exposome?

For those of us who are not scientists, we can use an additional section on what exposomes mean. Posted by molecular epidemiologist Christopher P. Wild in 2005, exposomes describe the synthesis of factors to which we are exposed that affect our health.

This explains how factors from our environment and lifestyle interact with our personal characteristics such as genetics and impact our health. Because while genetics play an important role in our health, they are only responsible for 20% of chronic diseases. Much of the rest is likely due to exposomes – making it a pretty big deal.

The good news is that although we can’t choose our genetics, we can update our lifestyle.

How does it affect your skin?

The skin is the largest organ in our body. At nearly 22 square feet, it’s the barrier between our bodies and the outside world. So naturally, our environment and daily lifestyle choices also affect the health and appearance of our skin. In fact, 80% of visible skin aging is caused by one manifestation factor: Ultraviolet ray.

80% of visible skin aging is caused by one manifest factor: UV radiation.

7 chromosomal factors that can harm your skin

Seven common physical and lifestyle factors can negatively affect skin health and appearance: sun exposure, smoking, weather, diet, stress, lack of sleep and pollution.

Let’s see how each of them affects our skin and How can we resist.

1. Your Solar Exposure

Sunny days are the best. But while soaking in the sun’s rays feels great and helps provide us with vitamin D, it is also The main cause of skin aging.

Solar radiation, and especially UV radiation, accelerates signs of skin aging (like dark spots and wrinkles) more than anything else in your exposomes. And not only that, it also increases the risk of skin cancer.

However, solar radiation isn’t just a seasonal concern. We are regularly exposed to UVA and UVB rays while sitting in cars, sitting in well-lit offices and even walking on cloudy days.

Solar radiation is the #1 culprit for visible skin aging.

How to fight:

Sunscreen, always. We visited the Head of Dermatology at the Beteré Clinic in Madrid, Spain, Dr. Paloma Borregón to be discovered by her expert: “The cream that I use every day is sunscreen. There is no better anti-wrinkle or anti-aging therapy than sunscreen.”

Get in the habit of applying a broad spectrum, high SPF sunscreen daily and remember to reapply every two hours. This simple step can help Fights 80% of signs of skin aging.

Protect against the biggest cause of skin aging with sunscreen

2. You smoke

Tobacco smoke contains more than 3,800 different harmful chemicals: nicotine, carbon monoxide, tar, ammonia, the list goes on. Smoking is a habit that is both bad for your health and bad for your skin.

Did you know that 10 years of smoking can make your skin 2.5 years older than normal? Wrinkles around the lips, crow’s feet, acne and gray skin are all side effects that your skin can live without.

10 years of smoking can add 2.5 years to your skin.

How to fight:

We are not here to judge. But when it comes to improving your skin and your overall health, Quitting smoking is the way to go.

3. Your Diet Could Be Better

Food plays an important role not only in our general health but also in the appearance of our skin. In fact, up to 30% of wrinkle formation can be related to diet. And sweets lovers everywhere beware: consuming too much sugar can also contribute to unwanted sugars.

Up to 30% of wrinkles can be attributed to poor nutrition.

How to fight:

We are what we eat. A healthy diet can improve our energy levels, mood and body from the inside out. So, following a varied, balanced diet can also improve our skin.

Vitamins and minerals help protect us from oxidative damage caused by free radicals and can help delay the appearance of aging skin. Reserve on Superfoods for your skin, such as seasonal fruits and vegetables, and cutting back on refined sugars will help you brighten up quickly.

4. You’re Stressing Your Skin

Our disliked emotions like stress and anxiety are also reflected in our skin. Stress can trigger skin conditions like eczema and acne, or worsen symptoms of existing problems like atopic or seborrheic dermatitis.

Cortisol is a hormone produced in response to stress. And high levels of cortisol can suppress your immune system, increase oxidative stress and impair your skin’s barrier function. So it’s no wonder Stress can correspond to skin discoloration, loss of elasticity and wrinkles.

Chronic stress can increase the appearance of skin discoloration and wrinkles.

How to fight:

It’s time to slow down and take a breather. Easier said than done, but to maintain the daily rhythm of life, we need to recharge our batteries. Take some time for yourself every day to do something that brings you joy. Try taking some calm time to take care of yourself and Be intentional when applying your skin care products.

Stress and cortisol levels can also be lowered through exercise or a good night’s sleep. Takes us to our next point…

5. You don’t get enough sleep

Busy schedules and scrolling at night can affect our mood and sleep. However, prioritizing rest is essential to both feeling and looking your best.

Lack of sleep can weaken the skin’s protective barrier and interfere with its response to other externally manifested factors. And sleeping less than five hours a day can actually increase annoying signs of skin aging like dull skin, dark circles under the eyes, and fine lines.

Sleeping less than 5 hours a day increases the signs of skin aging.

How to fight:

Fortunately, this is one of the exposomal factors that affect your skin maybe control.

At night, your skin goes from protection mode to repair mode to recover from the stresses of the day. Melatonin and human growth hormone (HGH) production is promoted, thereby accelerating skin regeneration and production of antioxidant enzymes. So catching a few extra z’s will naturally help your skin.

As if all of that weren’t promising enough, at night your skin will also be more receptive to topical skin care products, as it’s easier to absorb. Try an antioxidant-rich topical melatonin nightly routine, such as a rich serum, beauty sleeping cream, or even a nighttime eye cream for a completely rested look.

6. You are exposed to pollution

Every day we are exposed to high levels of pollution. Especially those of us who live in big, bustling cities. And pollution is part of our exposomes. closely related to the premature aging process of the skin.

Pollution from tobacco, heavy metals in the environment and CO2 emissions are just some of the main culprits. Their microparticles are suspended in the air and adhere to the skin. Over time, this can cause cellular damage from oxidative stress on your skin and increase the appearance of wrinkles, skin firmness and elasticity, dull skin and cause discoloration. unequal factors. In fact, many studies indicate that pollution is the main cause of dark spots. Sorry!

Studies show that pollution is the main cause of dark spots.

How to fight:

Incorporate good cleansing with rejuvenating products containing antioxidants into your daily skin care routine. Cleanse your skin daily, and especially at night, to get rid of pollution particles stuck around. Then add recovery antioxidants like vitamin C, found in Flavo-C Ultraglican Day Serum Tubes, and melatonin, in Melatonik 3-in-1 night serum, helps fight the signs of aging caused by oxidative damage.

7. You are exposed to extreme temperatures

You know what they say. If you can’t stand the heat… could your skin feel the same way? Excessive heat can cause oxidative damage, which contributes to premature aging of the skin.

Exposure to extreme heat has been linked to early signs of skin aging.

How to fight:

If your work depends on high temperature situations, there’s not much you can do here. But, a little proactive self-care can’t hurt. Try adding targeted exfoliating serums to help even skin tone and restore luminosity – Our skin lightening routine is a great place to start.


Healthy, radiant skin is a reflection of overall vibrant health. Focusing on how you can improve your daily experience with manifesting factors like sleep, pollution and diet can do wonders for your skin and health. And just for good measure, here are our favorite reminders again: Don’t forget to use sunscreen every day.

Presenter:

Khmaladze I, Leonardi M, Fabre S, Messaraa C, Mavon A. The Skin Interactome: A Holistic "Genome-Microbiome-Exposome" Approach to Understand and Modulate Skin Health and Aging. Clin Cosmet Investig Dermatol. 2020 Dec 24;13:1021-1040. doi: 10.2147/CCID.S239367

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