The process that leads to dry skin is complex and includes many factors with varying degrees of severity. These factors must be considered when creating a topical medication to help treat this skin problem. So, a 3-week moisturizing study on dry feet was done and published in the journal International Journal of Cosmetic Science.
The paper explains that the study included measurements of traditional and more recently developed biophysics methods to combine them with visual assessment of skin condition allowing multiple aspects of skin function to be determined. skin function. These methods were used to evaluate the effects of oils in water-based moisturizers against untreated skin during in vivo studies on dry foot skin.
There were statistically significant improvements demonstrated in skin hydration – as assessed by the Cornealometer (Epsilon) and visual dry skin classification, and skin barrier function – reported measured by transepidermal water loss. Other improvements seen were increased levels of cholesterol, free fatty acids and Ceramide NH. In addition, the mean length of the stratum corneum (SC) lipid bilayer and lipid-to-protein ratio increased—measured using Lipbarvis and In vivo Confocal Raman Spectroscopy, the paper further explains. Significant non-stationary changes were seen as increased Ceramide EOS and NP levels, along with an improvement in corneal cell maturation.
Use of the product resulted in significant improvements in skin barrier function and hydration, SC barrier lipid levels and morphology, and overall epidermal differentiation, the authors write. ,” the authors wrote. “The result was a significant reduction in the characteristics associated with the development of dry skin after using the test product.”
Stettler H, Crowther JM, Brandt M, et al. Target dry skin using a multifunctional topical moisturizer. Int J Aesthetic Science. In 2021; 43 (2): 191-200. doi: 10.1111 / ics.12680